Search on: ISLET AMYLOID POLYPEPTIDE 
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Descriptor English:   Islet Amyloid Polypeptide 
Descriptor Spanish:   Polipéptido Amiloide de los Islotes Pancreáticos 
Descriptor Portuguese:   Polipeptídeo Amilóide das Ilhotas Pancreáticas 
Tree Number:   D12.644.548.586.234
D12.776.049.407.500
Definition English:   A pancreatic beta-cell hormone that is co-secreted with INSULIN. It displays an anorectic effect on nutrient metabolism by inhibiting gastric acid secretion, gastric emptying and postprandial GLUCAGON secretion. Islet amyloid polypeptide can fold into AMYLOID FIBRILS that have been found as a major constituent of pancreatic AMYLOID DEPOSITS. 
Pharmacological Action:   Appetite Depressants
 
History Note English:   2011 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DU diagnostic use
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   54057 
Unique Identifier:   D058228 

Occurrence in VHL: 		 

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